The city has a diverse economy based on education, government, insurance, banking, defense, aviation, food, clothes, logistics, steel, energy, medical research, health care, hospitality, retail, and technology.Columbus is home to the Battelle Memorial Institute, the world's largest private research and development foundation; Chemical Abstracts Service, the world's largest clearinghouse of chemical information; Net Jets, the world's largest fractional ownership jet aircraft fleet; and The Ohio State University, one of the largest universities in the United States.
The area found itself frequently caught between warring factions, including American Indian and European interests.
In the 1740s, Pennsylvania traders overran the territory until the French forcibly evicted them.
under the nominal control of the French colonial empire through the Viceroyalty of New France from 1663 until 1763.
In the 18th century, European traders flocked to the area, attracted by the fur trade.
Early conditions were abysmal with frequent bouts of fevers and an outbreak of cholera in 1833.